摘要
目的总结原发性上尿路非移行细胞肿瘤的诊断、治疗和预后体会。方法回顾性分析本院1990年—2006年间,经病理证实的11例原发性上尿路非移行细胞肿瘤病例的临床病理特征、治疗及生存情况。结果本组11例,肿瘤位于肾盂8例,位于输尿管3例。均行手术治疗,术后病理证实鳞状细胞癌9例,腺癌1例,小细胞癌1例。10例分期为T3期或超过T3期,6例接受了辅助化疗,9例获得随访患者中7例死于全身转移,2例随访至今无瘤生存,中位随访时间是27个月,中位生存时间是8个月。结论原发性上尿路非移行细胞肿瘤临床罕见,大多数病人预后较差,可能与就诊时肿瘤已是晚期或对全身治疗反应较差有关。
Objective To summarize the experiences of diagnosis, treatment and prognosis in patients with nonurothelial origin tumors of upper urinary tract. Methods Clinical pathological characters, treatment and survival of 11 patients with primary nonurothelial tumors of upper urinary tract confirmed by pathological determination who had been treated in our hospital from 1990 to 2006 were retrospectively analyzed. Results Of 11 cases, tumors were located in the renal pelvis in 8 cases and in the ureter in 3 cases. 9 cases were proved to be squamous cell carcinoma, and 1 case was adenocarcinoma, and 1 case was small cell carcinoma by post-operative pathological determination. 10 cases of tumors were pathologic Stage T3 or worse. Six patients received adjuvant chemotherapy. Of 9 patients whose follow-up was available, 7 patients died of systemic metasis, however, 2 patients have survived without any recurrent tumor until now. The median follow-up was 27 months, and the median overall survival time was 8 months. Conclusion Primary nonurothelial carcinomas of the renal pelvis and ureter are rare. Poor prognosis in most patients is probably relative to diagnosis in the advanced stage and poor responses to systemic therapy of tumors.
出处
《杭州师范学院学报（医学版）》
2007年第2期75-77,共3页
Journal of Hangzhou Teachers College :Medical Edition
关键词
上尿路
非移行细胞肿瘤
upper urinary tract
nonurothelial origin tumor
