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眼部新生血管与抗血管内皮生长因子治疗 被引量：4

Anti-vascular endothelial growth factor treatment for ocular neovascularization
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摘要 眼部新生血管性病变是致盲的主要原因之一,可见于多种眼底疾病,其确切的发病机制尚不完全清楚。大量的研究证据表明血管内皮生长因子(VEGF)是新生血管形成的关键调控因子。本文对VEGF的特性、VEGF在眼部新生血管形成中的作用和抗VEGF治疗进行综述。 Ocular neovascularization is the primary cause of blindness in a wide range of ocular diseases. The exact mechanism underlying the pathogenesis of ocular neovascularization is not yet well understood. There is extensive evidence that vascular endothelial growth factor （VEGF） is a major regulator of neovascularization. The present paper focuses on VEGF and its role in ocular neovascularization and current anti-VEGF treatment.
作者 刘正 王业青 张晓梅
机构地区 哈尔滨医科大学第一临床医学院附属眼科医院
出处 《国际眼科杂志》 CAS 2007年第3期779-781,共3页 International Eye Science
基金 中国黑龙江省自然科学基金资助项目(No.D200662)~~
关键词 新生血管 血管内皮生长因子 治疗 neovascularization vascular endothelial growth factor treatment
分类号 R77 [医药卫生—眼科]
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参考文献20

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二级参考文献17

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共引文献11

同被引文献72

引证文献4

二级引证文献13

国际眼科杂志
2007年 第3期

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