摘要
目的 了解深圳市献血人群Rh（D）阴性稀有血型分布情况及基因频率。方法 采用Olympus PK7200全自动血型分析仪，对148253名献血人员进行Rh（D）阴性血型筛选，再经过间接抗球蛋白试验（IAT）确认，计算Rh（D）阴性稀有血型分布情况及基因频率。结果 共筛选确认Rh（D）阴性者519名，占0．35％；基因频率：d为0.0592，D为0.9408。结论 本市Rh（D）阴性者的分布频率与我国汉族Rh（D）阴性频率0、2％-0．5％相相吻合。但高于广东省汉族Rh（D）阴性频率0．197％，可能由于深圳市大部分人口是外省人迁移所致。
Objective To investigate the distribution and gene frequency for the Rh（D） - negative blood group of blood donors in Shenzhen. Methods Rh（D） - negative blood group was screened in 148253 donors with Olympus PK7200 analyzer and then confirmed by IAT test. Rh（D） - negative rare blood group distribution and gene frequency were calculated. Results Rh（D） - negative blood group was found in 519 donors, accounting for 0.35% ; Gene frequency was as follows ： d was 0. 0592, D was 0. 9408. Conclusion Rh （ D ） - negative blood group distribution frequency in Shenzhen is comparable with the Chinese Han nationality＇s frequency of 0.2 -0, 5%, but is higher than the Guangdong Han nationality＇s frequency of 0. 197%. The reason may be that most people in Shenzhen are immigrants from other provinces.
出处
《临床和实验医学杂志》
2007年第6期24-25,共2页
Journal of Clinical and Experimental Medicine
基金
2005年深圳市宝安区科技局资助顶目(2005183)
