摘要
[目的]通过对子宫乳头状浆液性腺癌(uterine papillary serous carcinoma,UPSC)的临床病例分析,探讨子宫乳头状浆液性腺癌的病因、诊断及临床病理特征。[方法]采用回顾性分析法,对1996年1月至2004年12月我校华西第二医院收治的30例子宫乳头状浆液性腺癌的临床病理特征、诊断、术后病理分期及治疗进行分析。[结果]24例患者同时记录了身高与体重,中体重指数(BMI)﹥32的18例(占75%)。全部病例采用手术治疗。手术病理分期I期10例(占33.3%),其中Ⅰa期3例,Ⅰb期3例,Ⅰc期4例;Ⅱ期7例(占23.3%),其中Ⅱa期3例,Ⅱb期4例;Ⅲ期为6例(占20%),其中Ⅲa,Ⅲb,Ⅲc期各2例;Ⅳ期7例(占23.3%),且均为Ⅳb期。30例中有15例(50%)已发生宫外转移。11例癌细胞分化程度为低分化者,其术后分期Ⅰ、Ⅱ、Ⅲ、Ⅳ分别为1、2、4、4例,而3例高分化者均为Ⅰ期;9例浅肌层浸润者2例(占22.2%)发生宫外转移,18例深肌层浸润者,13例(占72.2%)发生了宫外转移,两者之间的差异有统计学意义(P﹤0.05),提示肌层浸润程度越深,其宫外转移的可能性就越大。[结论]肥胖等因素与UPSC的发生有一定关系,癌细胞分化程度越低,其肌层浸润程度越深,宫外转移的可能性越大。
[Objective] To study pathogcnesis , diagnosis and clinical pathological features of uterine papillary serous carcinoma （UPSC） by analyzing some clinical cases. [Methods] Thirty casks of UPSC had been treated in our hospital between January .1996 and December. 2004, the pathogenesis, clinical pathologlcal teatures, diagnosis, treatment/and prognosis were retrospectively analyzed. [ Results] All the cases underwent operation, according to surgical pathological staging, 10 eases （accouming for 33.3%） were in stage Ⅰ , including three cases in stage Ⅰa., three cases in stage Ⅰb, four cases in stage Ⅰb, 7 cases （accounting for 23.3%） were in stage Ⅱ , including three cases in stage Ⅱa , four cases in stage Ⅱb, 6 cases （aceounting for 20%） were in stage Ⅲ, including two cases in stage Ⅲa, two eases in stage Ⅲa, two cases in stage Ⅲc; 7 cases （accounting for 23.3%） were in stage Ⅳb, 50% of all the thirty casks had transferred out of the uterine. [Conclusions] Obesity, diabetes mellitus, heredity factors have some correlation with UPSC. UPSC is really diagnosed by pathology. The deeper the muscle is infiltratted, the lower differentiation and bigher pathological staging it is.
出处
《现代预防医学》
CAS
北大核心
2007年第12期2367-2369,共3页
Modern Preventive Medicine
关键词
子宫内膜癌
乳头状浆液性腺癌
临床病理
手术病理分期
Endometrial carcinoma, Papillary serous carcinoma, Clinical pathology, Surgical pathological staging
