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比索洛尔在慢性阻塞性肺疾病中的应用 被引量:4

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摘要 目的:观察高选择性β-肾上腺素能受体阻滞剂比索洛尔对慢性阻塞性肺疾病(cOPD)患者心率及心、肺功能的影响。方法:将52例COPD患者随机分为两组:对照组继续抗感染等治疗,治疗组在上述治疗基础上加用比索洛尔2.5~5mg/d。监测心率及肺功能、血气分析,分别于治疗前和治疗后1年作超声心动图检查。结果:治疗组服用比索洛尔1周,心率明显减慢,服药1年后心率仍维持于较慢的水平,与治疗前相比,差异有极显著性(P〈0.001),左心室质量指数明显改善(P〈0.005,P〈0.001)。对照组心率无明显变化(P〉0.05),且一直偏快。结论:比索洛尔可使COPD患者心率明显减慢、左心室结构、功能明显改善,而又不进一步损害肺功能。
作者 裴野
机构地区 太原市中心医院
出处 《临床医药实践》 2007年第6期415-417,共3页 Proceeding of Clinical Medicine
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