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泌尿系感染患者血浆肿瘤坏死因子活性观察

Observation on plasma tumor necrosin activity of urinary system infection patient
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摘要 为探讨肿瘤坏死因子与泌尿系感染的关系,我们应用双抗体夹心ELISA法检测了24例泌尿系感染患者血浆肿瘤坏死因子,并与30例健康人对照。结果发现:1、泌尿系感染患者血浆肿瘤坏死因子明显高于健康对照组(P<0.05);2、感染患者经治疗后,血浆肿瘤坏死因子恢复至正常水平;3、泌尿系统感染患者血浆肿瘤坏死因子活性变化与其它临床症状及尿液检查相一致。结果提示:肿瘤坏死因子参与炎症的病理过程。急性炎症时,应考虑细胞因子所起的作用。 24 cases of plasma tumor necrosin of urinary system infection patients were detected with double antibody sandwich ELISA method and compared with 30 cases of healthy persons. The result shows:1. Plasma tumor necrosin of urinary system infection patient is significantly higher than healthy contrast group (p < 0.05 ); 2. After treatment, the plasma tumor necrosin of infected patient returned to normal level; 3. The change of plasma tumor necrosin activity of urinary system infection patient is consistent with other clinical symptoms and examined substance of urine.The result points out that tumor necrosin participates in pathological process of inflammation.
机构地区 解放军第
出处 《西藏医药》 1997年第3期24-25,共2页 Tibetan Medicine
关键词 泌尿系感染 血浆肿瘤坏死因子(TNF_α) 急性炎症 urinary system infection,plasma tumor necrosin
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参考文献1

  • 1汪江淮,王正国.TNF在内毒素/感染性休克发病机理中的作用[J]第三军医大学学报,1992(01).

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