摘要
应用食管心房调搏术（ＴＥＡＰ）观察心律平对５０例阵发性室上性心动过速的急性电生理效应。结果表明：心律平对房室旁道和房室结双径道均有明显的抑制作用，以旁道尤为明显。该药能阻断旁道的前向和逆向传导，延长其不应期。并使房室结传导的文氏阻滞点和２：１阻滞点提前，从而有效终止心动过速的发作。
Trans esophagus atrial pacing (TEAP) was employed to evaluate the acute electrophysiological effects of propafenone administrated intravenously in 50 patients with SVT. Forty three of the subjects are patients with atrial ventricular reciprocating tachycardia (AVRT). Seven of them were involved in atrioventricular nodal reentry tachycardia (AVNRT). The results indicate that propafenone exerts an obvious inhibitory effect on both the dual atrioventricular node pathways and the accessory pathways, with the latter one being markedly affected. In addition, propafenone can deter the antegrade and retrograde conduction and prolong the refractory period of the accessory pathways. Still more, it results in preceding of the Wenchebach and 2 to 1 block point of the atrioventricular node conduction. All these promise the potential terminating effect on tachycardia. Propafenone has little effects on sinus node. Prolongation of sinus node recovery time (SNRT) to 3600ms following drug administration was observed in only one patient who has a history of sinus bradycardia.
出处
《湖南医科大学学报》
CSCD
1997年第2期123-126,共4页
Bulletin of Hunan Medical University
关键词
心动过速
室上性
食管心房调搏
心律平
电生理学
tachycardia
supraventricular
propafenone
transesophageal atrial pacing *
electrophysiology
