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哌替啶预防雷米芬太尼停药后疼痛的可行性观察

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摘要 目的研究哌替啶预防雷米芬太尼停药后急性疼痛的可行性。方法择期腹腔镜手术病人40例,随机分为两组,每组20例。P组在停药前5min静脉注射哌替啶1mg/kg;F组在停药前5min静脉注射芬太尼0.2mg。观察术后疼痛视觉模拟评分,监测术前(T0)、术毕停药时(T1)、术后5min(T2)、术后10min(T3)、术后15min(T4)、术后30min(T5)的MAP、HR、SpO2。结果两组患者术前与术毕停药后的MAP、HR、SpO2无明显差异。两组患者的VAS评分无显著性差异(P>0.05),均显示有镇痛效果。术毕拔管时间P组平均为15min,F组平均为30min,两组患者无明显呼吸抑制、烦躁、恶心、呕吐等并发症。结论哌替啶预注可以有效预防雷米芬太尼停药后的急性疼痛,不影响术后拔管时间,无明显并发症。
作者 周燕
机构地区 江苏省常州市第一人民医院麻醉科
出处 《齐齐哈尔医学院学报》 2007年第8期920-921,共2页 Journal of Qiqihar Medical University
关键词 雷米芬太尼 哌替啶 芬太尼 全凭静脉麻醉
分类号 R971.1 [医药卫生—药品]
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参考文献4

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齐齐哈尔医学院学报
2007年 第8期

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