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肺癌发病及骨转移相关因素分析 被引量:1

The Study on the Related Factors with Lung Cancer and Osseous Metastasis
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摘要 目的:探讨肺癌发病的可能相关因素。方法:选择87例确诊为肺癌的患者,收集患者的一般资料,临床信息以及诊断和治疗信息,其中伴骨转移者39例。结果:发病年龄平均67.8岁;6例(35.3%)女性患者为吸烟者,58例(97.7%)男性患者有吸烟史。女性吸烟人数及吸烟量增多;咳嗽为最常见的症状;病理组织学男性患者多为鳞癌,女性腺癌多见;Ⅲ和Ⅳ期明显多于Ⅰ期和Ⅱ期。虽然外科手术治疗后可以提高患者生存时间,接受外科手术患者仍较少。骨转移与性别、年龄和放化疗与否无关,与病理类型有关。结论:年龄、吸烟与肺癌发病密切相关,多数患者就诊时为中晚期,多只能接受姑息治疗,早期诊断及其重要。腺癌患者需警惕骨转移。 Objective: To study the factors possibly related to lung cancer. Methods: Eighty seven patients diagnosed with lung cancer were obtained, including 39 cases with osseous metastasis as well, and their epidemiological, clinical, diagnostic, and therapeutic variable was assessed. Results: The mean age of patients was 67.8. 35.3% female patients were smoker while 97.7% in men. More women patients were smoker, and the number of cigarettes increased. Cough was the most common symptom. Pathohistology showed that male patients were associated with squamous carcinoma whereas females associated with adenocarcinoma. Cases of phase Ⅲ and Ⅳ were obviously more than those of phase Ⅰ and Ⅱ. Although treatment with surgery could increase the survival of patients, the percentage of patients undergoing surgery is very low. There was relationship between bone metastasis and adenocarcinoma, but not sex, age and radiotherapy or chemotherapeutics. Conclusion: Age and cigarette were closely correlated with lung cancer. Most of the patients could only receive palliative treatment because they got diagnosed at the late stage of lung cancer. Therefore, earlier discovery was very important for patients with lung cancer. Patients with adenocarcinoma should espedally be cautious to osseous metastasis.
出处 《现代生物医学进展》 CAS 2007年第7期1072-1073,1080,共3页 Progress in Modern Biomedicine
基金 湖南省卫生厅资助项目(C2003-014)
关键词 肺癌 骨转移 相关因素 Lung cancer Osseous metastasis Related factors
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