摘要
目的:探讨HLA-G5表达与器官移植排斥之间的关系。方法:应用酶联免疫方法检测移植术后2个月以上的50例肝移植受者和60例肾移植受者外周血HLA-G5的表达情况。结果:肝、肾移植受者中HLA-G5阳性表达受者的急慢性排斥反应发生率明显低于阴性表达受者。结论:HLA-G5的表达与肝、肾移植受者排斥反应发生率的降低密切相关。
Objective： To search the relationship between HLA-G5 expression and rejection of organ transplantation. Methods： Of the recipients, who received organ transplantation at least 2 months, including 50 cases of liver recipients and 60 cases of kidney recipients, the expression of HLA-G5 was measured in the sera of recipients by enzyme-linked immunosorbent assay（ELISA）. Results： For both liver and kidney recipients, acute rejection（AR） accidence rate of HLA-G5 positive（HI,A-G5^＋） group was higher than that of HLA-G5 negative（HLA-G5^-） group（P〈0.05）; chronic rejection（CR） accidence rate of HLA-G5^＋ group was lower than that of HLA-G5^- group（P〈0.05）. Conclusion： HLA-G5 expression is associated with lower rejection episodes of liver or kidney recipients.
出处
《生物技术通讯》
CAS
2007年第2期258-259,共2页
Letters in Biotechnology
