摘要
目的:观察维生素B_(12)+卡马西平的联合治疗与卡马西平单独治疗原发性三叉神经痛的临床效果。方法:采用随机、对照、开放性临床试验。入选42例原发性三叉神经痛患者,随机分为维生素B_(12)+卡马西平联合治疗组与卡马西平单独治疗组,应用目测类比疼痛评分对疼痛进行评估并比较治疗前后的效果。结果:联合治疗对原发性三叉神经痛的止痛效果明显。结论:联合药物治疗三叉神经病是一种非常有效和安全的治疗方法,值得进一步研究。
Objective：To evaluate the clinical effects of carbamazapine combining with vitamin B12 in the treatment of patients with primary trigeminal neuralgia. Methods： This was a radomized control, open-label clinical trial. Choose patients who have the primary trigeminal neuralgia to evaluate their ache degree and compare the effect before therapy with after one, then analyze the data with Wilcoxon signed-rank test. Results： The combination therapy has marked clinical effects in releasing pain of primary trigeminal neuralgia. Conclusion： The combination therapy is an effective and safe method, which is valuable to study more.
出处
《中国临床医学》
北大核心
2007年第3期388-389,共2页
Chinese Journal of Clinical Medicine
