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超排卵对小鼠卵母细胞和胚胎发育潜能的影响 被引量:10

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摘要 目的比较超排卵对小鼠卵母细胞和胚胎发育潜能的影响。方法建立超排卵妊娠小鼠模型,获取孕4d胚胎,观察获取卵母细胞的数目、受精率、卵裂率、优质胚胎率和囊胚形成率,并与自然周期排卵小鼠的比较。结果超排周期组获取的卵母细胞的数目高于自然周期组;超排周期组的受精率(88.57%)和卵裂率(92.17%)与自然周期组的受精率(92.86%)和卵裂率(96.70%)相似,但超排周期组的优质胚胎率(76.50%)和囊胚形成率(22.50%)低于自然周期组的优质胚胎率(88.64%)和囊胚形成率(43.18%)。结论超排卵能增加卵母细胞和胚胎的数量,不影响受精和卵裂,但会降低优质胚胎率和囊胚形成率,影响卵裂后胚胎的进一步发育的潜能。
出处 《四川大学学报(医学版)》 CAS CSCD 北大核心 2007年第4期725-727,共3页 Journal of Sichuan University(Medical Sciences)
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