摘要
与非小细胞肺癌相比较,小细胞肺癌具有更快的肿瘤倍增时间、快速生长以及易于早期转移的特点。以往认为小细胞肺癌的患者不适合手术,小细胞肺癌的主要治疗是化疗和放疗。但是许多研究表明手术对于早期局限型的小细胞肺癌患者有益,特别是T2N0的患者,同时手术治疗能够防止其局部复发。但临床分期超过T2N0的患者,手术无益于患者的长期生存。对于手术治疗适合哪一期小细胞肺癌的患者、手术如何联合化疗以及手术的方式仍然值得进一步研究。
Compares with non-small cell lung cancer, small cell lung cancer （SCLC） generally has a more rapid doubling time, a higher growth fraction, and earlier development of widespread metastases. Surgical operation has little impact on long-term survival of SCLC patients. Chemotherapy with combined radiotherapy has been recommended as the main treatment of SCLC. Patients with SCLC in excess of stage T2NO do not benefit from surgical operation, But some data suggest the potential benefit of surgcial resection in the few patients with very limited disease, especially peripheral T1-2NO lesions. Surgical resection can also prevent the recurrence of local disease. The role of surgical resection in the management of SCLC remains to be defined.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
2007年第7期795-797,共3页
Chinese Journal of Cancer
关键词
肺肿瘤/外科手术
小细胞肺癌
疗效
Lung neoplasm/surgical operation
Small cell lung cancer
Efficacy
