摘要
目的评价患者院内使用他汀类药物治疗对冠状动脉血运重建患者院内临床结果的影响。方法3763例冠状动脉血运重建(PCI或CABG)患者根据院内是否使用他汀类降脂药物分为他汀治疗组与非他汀治疗组,对两组院内临床结果进行回顾性分析比较。结果非他汀治疗组患者的病死率(3.1%)、不良心脑血管事件发生率(4.3%)均明显高于他汀治疗组(1.4%、2.0%)。年龄、左室射血分数、住院使用阿司匹林以及住院使用他汀类药物是预测血运重建患者院内不良事件的危险因素。结论早期开始他汀类药物治疗有利于降低冠心病血运重建患者院内不良事件的发生率。
[Objective] To evaluate the impact of statins on inhospital clinic outcomes in patients undergoing coronary revascularizatlon. [Methods] 3763 patients underwent coronary revascularization were randomly divided into two groups according to whether using statins or not. [Results] 2360 patients were treated with statins during hospital, and 1403 patients were treated without statins. 44 patients（3.1%） died in non-statlns group, 33 patients（1.4%） died in statins group, and the rates of main adverse cardiac cerebral events were high among statins nonusers （4.3% vs 2. 0% ,P〈0.01）. Logistic regression showed that age, left ventricular ejection fraction, using Aspirin and using statins during hospital were the risk predictor for hospital adverse clinic outcomes. [Conclusion] Early statins use reduces the hospital rate of adverse clinic events in patients undergoing coronary revascularization.
出处
《山东医药》
CAS
北大核心
2007年第7期9-10,共2页
Shandong Medical Journal
基金
国家重点基础研究发展规划资金资助项目(973计划)(2003CB17103)
