摘要
采用细胞病变效应(CPE)抑制实验观察和分析低浓度Zn2+、Cu2+和Mn2+金属离子对病毒的抑制作用。低浓度Zn2+在体外有较好的抑制单纯疱疹病毒、呼吸道合胞病毒和副流感病毒的致病作用;低浓度Cu2+和Mn2+在体外有较好的抑制副流感的致病作用。研究表明,将金属离子进行复合不但可以提高抑制作用,而且可以降低单一离子的浓度。
The cytopathic effect (CPE) inhibitory assay tests were used to investigate the antiviral effect of low concentration metal ions on virus in vitro. Zn^2+ at low concentration had significant antiviral effect against herpes simplex virus, respiratory syncytial virus and parainfluenza virus: Cu^2+ and Mn^2+ at low concentration had significant antiviral effect against parainfluenza virus: the mixture of metal ions had significant antiviral effect against herpes simplex virus, respiratory syncytial virus and parainfluenza virus even if the concentration of each ion was lower. The mixture of Zn^2+, Cu^2+ and Mn^2+ not only reduced the concentration when they were used separately, but also enhanced the antiviral activity.
出处
《食品工业科技》
CAS
CSCD
北大核心
2007年第6期110-112,共3页
Science and Technology of Food Industry
基金
吉林省科技发展基金(20020503-2)。