摘要
目的:建立猪肺表面活性物质冻干粉的粒度分析方法。方法:分别测定了以0.9%氯化钠溶液及蒸馏水为分散介质时样品混悬液的粒度分布情况,同时辅以 Zeta 电位测定以考察样品混悬液的稳定性。结果:以蒸馏水为分散介质时样品的分散效果较好。结论:本方法可快速、简单、准确地测定猪肺表面活性物质冻干粉混悬液的粒度分布。
Objective： To develop a method for the determination of the particle size of porcine pulmonary surfactant lyophilized powder. Methods： Determine the particle size of the sample dispersed in 0. 9% sodium chloride solution and in distilled water respectively and measure the Zeta potential to evaluate the stability of these two suspensions. Results：The sample is dispersed more effectively in distilled water. Conclusions：This method can be used for the determination of the particle size of the suspension of porcine pulmonary surfactant lyophilized powder and it is fast, simple and accurate.
出处
《药物分析杂志》
CAS
CSCD
北大核心
2007年第6期863-866,共4页
Chinese Journal of Pharmaceutical Analysis
关键词
猪肺表面活性物质冻干粉
激光散射粒度分析
ZETA电位
porcine pulmonary surfactant lyophilized powder
laser scattering particle size distribution analysis
Zeta potential
