摘要
对四川省叙永县碘缺乏病区学生血清中超氧化物歧化酶（ＳＯＤ）和脂质过氧化物（ＬＰＯ）含量测定的结果表明，碘缺乏病区学生血清中ＳＯＤ含量明显下降和ＬＰＯ含量增加的现象，与对照组间有显著性差异（Ｐ＜０．０１）。通过对碘缺乏与机体脂质过氧化相互关系的初步探讨，认为由碘缺乏引起的机体中ＳＯＤ含量减少和ＬＰＯ含量增加，将可能导致甲状腺细胞膜的损伤，甲状腺功能障碍。
The SOD and LPO contents were determind in serum obtained from students of IDD area, Xuyong. The result showed that there were decrease of the SOD and increase of the LPO contents in serum,and significant differences could be found between the IDD area and non-endemic area(P<0.01). By preliminary investigation of interrelation between iodine deficiency and lipid peroxidation, we uconsidered that iodine deficiency resulted in increase of LPO content and decrease of SOD content ,which would cause CM damage and functional disorder in thyroid.
出处
《中国地方病学杂志》
CAS
CSCD
1997年第2期79-80,共2页
Chinese Jouranl of Endemiology
