摘要
哈蟆油能抑制氢化可的松致肾虚小白鼠的体温下降及体重减轻，而对正常小白鼠体重无影响．能延长肾虚小鼠的滚棒及游泳时间，常压耐缺氧的存活时间略有延长，以哈蟆油的作用最明显，石油醚提取物次之，甲醇提取物作用不明显．哈蟆油能延长正常动物的爬杆、滚棒、游泳时间，石油醚提取物１３６ｍｇ／ｋｇ作用明显，６８ｍｇ／ｋｇ作用不明显，甲醇提取物的作用以小剂量组８５ｍｇ／ｋｇ作用明显，１７０ｍｇ／ｋｇ次之．
The effects of Oviductus Ranae(O.V) and the component extracted from OV MeOH and Pet.Et on mice with kidney Yin deficiency were evidenced.The result shows that OV at the dose of 680 mg/kg·d×7 i.g.can singnificantly inhibit the fall of body temperature,prolong the duration of swimming and rolling inhibit slightly the decrease of body weight and prolong slightly the duration of Normobaric hypoxic mice with kidney Yin deficiency induced by hydrocortisone.The effect of Pet.Et extract at 136 mg/kg·d×7 i.g.is similar to the above,but the effect of MeOH extract is not significant. There is not significant difference between the effectso of MeOH and Pet.Et extract in normal mice.
出处
《沈阳药科大学学报》
CAS
CSCD
1997年第1期20-23,共4页
Journal of Shenyang Pharmaceutical University
关键词
喻蟆油
石油醚提取物
甲醇提以物
肾阴虚
Ovductus Ranae
Hydrocortisone
Pet.Et of O.V
MeOH extract of O.V
Kidney ren deficiency
