摘要
目的探讨青少年甲亢的治疗方法。方法取7～17岁青少年甲亢患者167例,分为131碘治疗组(131I组)79例和抗甲状腺药物治疗组(ATD组)88例两组,分别进行疗效、甲状腺功能低下(甲低)发生率及复发率、突眼发生率的比较。结果131I组治愈56例(70.88%),好转16例(20.25%),无效7例(8.86%);ATD组治愈25例(28.41%),好转43例(48.86%),无效20例(22.73%)。两组疗效比较,131I组明显高于ATD组(P<0.01)。发生突眼及突眼缓解率两组差异无显著性(P>0.05)1。31I组甲低发生率高于ATD组(P<0.05),治愈后甲亢复发率低于ATD组(P<0.05)。结论131I治疗青少年甲亢效果优于ATD,是一种疗效肯定、比较安全的方法。
Objective To investigate an effective therapy for the treatment of adolescent hyperthyroidism. Methods 167 adolescents with hyperthyroidism aged 7-17 years were allocated to ^131Iodine （^131I） group （79 cases） and antithyroid drugs （ATD） group （88 cases）. A comparison of curative efficacy, incidence of hypothyroidism, relapse and exophthalmos between these two groups were performed. Results In ^131I group, 56 cases （70.88 % ） were found with complete remission, 16 cases （20.25%） with improved remission, 7 cases （8.86%） with no response. In ATE） group, 25 cases （28.41% ） were found with complete remission, 43 cases （48.86%） with improved remission, 20 cases （22.73%） with no response. Compared to ATD group, the curative efficacy in ^131I group was higher, P〈0.01. In comparison of the incidence of exophthalmos and the its remission rate between these two groups, there was no statistically significant difference （ P 〉0.05）. Compared to ATD group, the incidence of hypothyroidism was higher in ^131I group （ P 〈0.05）, after healing, relapse of hyperthyroidism in ^131I group was lower （ P 〈0.05）. Conclusion ^131I is effective and safe in treatment of adolescent hyperthyroidism, which is superior to ATD.
出处
《右江民族医学院学报》
2007年第4期511-513,共3页
Journal of Youjiang Medical University for Nationalities
