摘要
目的 探讨乳腺癌化疗患者癌因性疲乏状况及其影响因素。方法 随机选取接受化疗前3个疗程的符合乳腺癌诊断患者110例，于化疗前1～2d、化疗中5～7d、化疗后5-7d3个时间点进行癌因性疲乏的测量。结果 化疗中和化疗后，乳腺癌患者的癌因性疲乏属于中等程度，化疗前、中、后的疲乏程度差异有统计学意义（F=45．19，P〈0．01），化疗后5～7d疲乏最重。化疗前、中、后疲乏程度的发生率差异有统计学意义（Hc=52．0625，P〈0．01）。影响癌因性疲乏的因素化疗前有医疗方式（t=2．24，P〈0．05）、化疗方案（t=2．18，P〈0．05）和疗程（t=3．59，P〈0．01）；化疗后有医疗方式（t=2．53，P〈0．05）和化疗方案（t=2．21，P〈0．05）。结论 护理人员应关注和重视癌因性疲乏，尤其是应加强对化疗中5～7d患者癌因性疲乏的关注和指导，使护理干预更有依据和针对性。
Objective Discussing the related factors of cancer-related fatigue among patients with breast cancer when cured by chemotherapy. Methods Selected 110 patients with breast cancer who had accepted 3 periods of treatment of chemotherapy, evaluted cancer-related fatigue among them at the time points of 1 -2 days before chemotherapy, 5-7 days during chemotherapy and 5-7 days after chemotherapy and then analyzed the related factors of cancer-related fatigue. Results Conditions about cancer-related fatigue during and after chemotherapy were worse, there was significant difference among the three time points about cancer-related fatigue, F=45.19,P〈0.01. Conclusions Cancer-related fatigue should be emphasized by nurses, especially during chemotherapy, which can effectively improve the pertinence for nursing intervention.
出处
《中国实用护理杂志》
2007年第6期1-4,共4页
Chinese Journal of Practical Nursing
基金
安徽省高等学校省级自然科学研究项目（2006KJ121C）,志谢本文承蒙中国香港Winnie博士指导
关键词
乳腺癌
化疗
癌因性疲乏
Breast cancer
Chemotherapy
Cancer-related fatigue
