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性别对青少年特发性脊柱侧凸患者手术疗效的影响 被引量:7

Does gender affect the surgical result of adolescent idiopathic scoliosis?
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摘要 目的:比较男女性青少年特发性脊柱侧凸(AIS)患者后路内固定融合术后及1~3年随访的矫形效果,探讨性别对AIS手术疗效的影响。方法:1999年~2004年在我院手术治疗的LenkeⅠ型AIS患者56例,女性35例,平均年龄15.4岁,平均Cobb角58.0°,术后平均随访22个月;男性21例,平均年龄16.0岁,平均Cobb角63.2°,术后平均随访20个月。所有患者均在全麻下行后路矫形内固定融合术,分别记录手术时间、失血量、输血量、固定节段数及并发症,分别测量术前、术后早期及末次随访时主弯Cobb角,比较两组患者的差异。结果:男女性患者平均手术时间分别为266min和258min,术中平均失血量分别为1689ml和1343ml,输血量分别为1148ml和919ml,固定节段数分别为10.9个和10.7个,并发症发生率分别为8.6%和19.0%,两组间无明显差异;术后平均Cobb角分别为26.4°和27.5°,平均矫正率分别为54%和56%,末次随访时平均Cobb角为27.3°和29.5°,平均矫正率分别为46%和45%,矫正丢失分别为4.3°和6.2°,两组比较无统计学差异。结论:男女性AIS患者在术后及1~3年随访的矫形效果、手术相关参数及并发症发生率均无明显差异,性别对AIS患者手术疗效无明显影响。 Objective:To compare the post-operative and 1 to 3 year's follow-up clinical results of male and female adolescent idiopathic scoliosis(AIS) patients who underwent posterior instrumentation,so as to evaluate the affection of gender on surgical treatment.Method:Fifty-six patients with Lenke Ⅰ type AIS underwent posterior instrumentation between 1999 and 2004.Thirty-five girls with mean age 15.4 years old,mean Cobb angle 58.0° and mean follow-up 22 months while 21 boys with mean age 16.0 years old,mean Cobb angle 63.2° and mean follow-up 20 months.The standing long-cassette anteroposterior and lateral radiographs of spine were taken before and after surgery and during follow-up.The Cobb angle of major curve was measured and the pre- and intra-operative parameters were recorded.Result:The mean operative time was 266 minutes for the female patients with average 10.9 instrumented levels and 258 minutes for male patients with average 10.7 instrumented levels.The intra-operative blood loss and transfusion were 1689ml and 1148ml separately in girls as well as 1343ml and 919ml in boys.The complication rates were 8.6% in girls and 19.0% in boys.Although there are slightly differences in most of radiographic and operative parameters ,all of them have no significance.In female patients,the mean Cobb angle of major curves immediately after surgery was 26.4° with mean correction of 54% and the mean Cobb angle in final follow-up was 27.3° with mean correction of 46% as well as the correction loss of 4.3°.While in male patients,the mean Cobb angle of major curves immediately after surgery was 27.5° with mean correction of 56% and the mean Cobb angle in final follow-up was 29.5° with mean correction of 45% as well as the correction loss of 6.2°.Conclusion:No significant differences in radiographic and operative parameters are found between male and female patients and the gender have no significant effect on surgical treatment.
出处 《中国脊柱脊髓杂志》 CAS CSCD 2007年第7期503-506,共4页 Chinese Journal of Spine and Spinal Cord
基金 江苏省卫生厅科研重大项目(编号:K200610)
关键词 青少年特发性脊柱侧凸 性别 手术疗效 Adolescent idiopathic scoliosis Gender Surgical outcome
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参考文献12

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