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肿瘤与水通道蛋白关系的研究进展 被引量:2

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摘要 水通道蛋白(AQPS)属于疏水性蛋白质,是一种能促进水转运的小分子跨膜蛋白家族。它几乎在所有的活体中均有表达,并在控制水流进或流出细胞方面起着重要作用。目前,在哺乳动物身上已经发现了13种AQP(AQP0-12),它们都有着重要的生理和病理意义。现将AQPS及其与肿瘤关系的一些研究进展作一综述。
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2007年第7期891-892,共2页 Chinese Journal of Experimental Surgery
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  • 1Hu J,Verkman AS. Increased migration and metastatic potential of tumor cells expressing aquaporin water channels. FASEB J ,2006,20 : 1892-1894.
  • 2Jeyaseelan K, Sepramaniam S, Armugam A, et al. Aquaporins : a promising tar- get for drug development. Expert Opin Ther Targets,2006,10:889-909.
  • 3Yasui M. Molecular mechanisms and drug development in aquaporin water channel diseases:structure and function of aquaporins. J Pharmacol Sci, 2004, 96 : 260- 263.
  • 4Anthon'y TL, Brooks HL, Boassa D, et al. Cloned human aquaporin-1 is a cyclic GMP-gated ion channel. Mol Pharmacol, 2000,57:576-588.
  • 5Endeward V, Musa-Aziz R, Cooper GJ, et al. Evidence that aquaporin 1 is a major pathway for CO2 transport across the human erythrocyte membrane. FASEB J, 2006,20 : 1974-1981.
  • 6Nakhoul NL, Hering-Smith KS. Transport of NH3/NH in oocytes expressing aqua- porin-1. Am J Physiol Renal Physiol, 2001,281:255-263.
  • 7Liu Z, Shen J, Carbrey. Arsenite transport by mammalian aquagly- ceroporins AQP7 and AQP9. Proc Natl Acad Sci USA, 2002,99:6053-6058.
  • 8Yasui M, Kwon TH, et al. Aquaporin-6 : an intracellular vesicle water channel protein in renal epithelia. Proc Natl Acad Sci USA, 1999,96:5808-5813.
  • 9Takaia K, Matsuzaki T, Tajika Y, et al. Aquaporins :water channel proteins of the cell membrane. Prog Histochem Cytochem ,2004,39 : 1-83.
  • 10Zelenina M,Tritto S, Bondar AA, et al. Copper inhibits the water and gly- cerol permeability of aquaporin-3. J Biol Chem, 2004,279:51939-51943.

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  • 1Huang Q,Liu XZ,Kang CS,et al.The anti-glioma effect of suicide gene therapy usingBMSC expressing HSV/TK combined with o-ver expression of Cx43 in glioma cells.Canc-er Gene Ther,2010,17:192-202.
  • 2Gaynor JW, Campbell BJ, Cosstick R. RNA interference., a chemist's perspective[J]. Chem Soc Rev, 2010,39 ( 11 ) :4169-4184.
  • 3E1 Hindy N,Bankfalvi A, Herring A, et al. Correlation of aquaporin-1 water channel protein expression with tumor ~ngiogenesis in human astroeytoma[J]. Anticancer Res, 2013,33(2) :609-613.
  • 4Hu J, Verkman AS. Increased migration and metastatic potential of tumor cells expressing aquaporin water chan- nels[J]. FASEB J, 2006 (20) : 1892-1894.
  • 5Jeyaseelan K, Sepramaniam S, Armugam A, et al. Aqua- porins:a promising target for drug development[J]. Ex- pert Oaoin Ther Targets,2006(10):889-909.
  • 6Itoh T,Rai T,Kuwahara M,et al. Identification of a novel aquaporin, AQP12, expressed in pancreatic acinar cells [J]. Biochem Biophys Res Commun, 2005,330 (3) : 832- 838.
  • 7Mobasheri A,Airley R, Hewitt SM, et al. Heterogeneous expression of the aquaporin 1 (AQP1) water channel in tumors of the prostate, breast, ovary, colon and lung: a study using high density multiple human tumor tissue mi- croarrays[J]. Int J Oncol,2005,26(5) :1149-1158.
  • 8Yang J H, Shi YF, Cheng Q, et al. Expression and localiza- tion of aquaporin-5 in the epithelial ovarian tumors[J]. Gynecol Oneol,2006,100(2) :294-299.
  • 9Endo M,Jain RK, Witwer B, et al. Water channel (aqua- porin 1) expression and distribution in mammary carcino- mas and gliblastomas[J]. Microvase Res, 1999,58 (2): 89- 98.
  • 10Saadoun S, Papadopoulos MC, Davies DC, et al. Increased aquaporin 1 water channel expression in human brain tumours[J]. Br J Cancer,2002,87(6) :621-623.

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