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替米沙坦对原发性高血压左心室肥厚的影响

The Effect of Telmisartan in Reversing Left Ventrictlar Hypertrophy in Essential Hypertension Patients
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摘要 目的评价替米沙坦在治疗原发性高血压中逆转左心室肥厚及改善左心室舒张功能的疗效。方法选择56例原发性高血压病且有左心室舒张功能受损的患者,评价治疗6个月后左心室肥厚的逆转程度及左心室舒张功能的改善状况。结果与治疗前比较,LVDd、IVST、LVpwT均下降,E/A比值显著增加,替米沙坦逆转左心室肥厚及改善左心室舒张功能差异显著(P<0.01)。结论替米沙坦是一种理想的抗高血压及逆转左心室肥厚的药物。 Objective To evaluate the effect, of Telmisartan in reversing left ventrictlar hypertrophy and improving the diastolic function of left ventricle. Methods 56 patients suffering from hypertension with the damage of diastolic function of left ventricle were chosen, to evaluate the reverse degree of left ventricular hypertrophy and the improvement of the diastolic function of left ventricl after 6 months. Results Compared with prior treatment, LVDd, IVST, LVpwT, LVMI decreased seriously, but the E/A rate increased remarkably. There was significant statistical difference in Telmisartan about reversing left ventricular hypertrophy and improving the diastolic function of left ventricle(P 〈0.01 ). Conclusions Telmisartan is a ideal antihypertensive medicament with the effect of reversina the left ventricular hypertrophy.
作者 刘珊
机构地区 恩施市中心医院
出处 《湖北民族学院学报(医学版)》 2007年第2期38-39,共2页 Journal of Hubei Minzu University(Medical Edition)
关键词 替米沙坦 高血压 左心室肥厚 Telmisartan Hypertension Left ventricular hypertrophy
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