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小剂量倍他乐克与培哚普利联用治疗充血性心力衰竭临床观察 被引量：1

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摘要 目的：探讨倍他乐克在治疗充血性心力衰竭中能否增强血管紧张素转换酶抑制剂（ACEI）的疗效。方法：选择心功能Ⅱ-Ⅲ级心力衰竭病人随机分为两组，对照组单用培哚普利片每日4mg，观察组用培哚普利片每日4mg联用倍他乐克片每日12．5mg，疗程4周，观察治疗前后病人收缩压、心率和左心室射血分数的变化。结果：用药治疗4周后对照组和观察组病人的收缩压、心率都比用药前明显下降（P〈0．05），而左心室射血分数明显升高（P〈0．05），观察组比对照组改变更为显著（P〈0．01）。结论：倍他乐克和培哚普利联用治疗充血性心力衰竭能有效地降低血压和改善心功能状态。
作者 宋淑敏
机构地区 包钢第三职工医院内科
出处 《包头医学院学报》 CAS 2007年第3期259-260,共2页 Journal of Baotou Medical College
关键词 倍他乐克 培哚普利 充血性心力衰竭
分类号 R541.6 [医药卫生—心血管疾病]
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参考文献11

  • 1Jafri SM,Gheorghiade M,Levine TB,et al.Effects of vasodilator therapy on survival in patients with chronic heart failure[J].Prog Cardiovasc Dis,1992,35:213-215.
  • 2Cohn JN,Johnson G,Ziesche S,et al.A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chnonic corgestive heart failure[J].N Engl J Med,1991,325:303-305.
  • 3李德之.心力衰竭时β－阻滞剂应用的原则与经验[J].中国实用内科杂志,1994,14(2):75-76. 被引量：70
  • 4Davis JO.Mechanisms of salt and water netention in congestine heart failure.The role of aldoserone[J].Am J Med,1960,29:486-487.
  • 5Kluger J,cody RJ,Laragh JH.The contributions of sympathetic tone and the rennin angiotensin system to severe chronic congestive heart failure:Response to specific inhibitors (Prazosin and captopril)[J].Am J Cardiol,1982,49:1667-1669.
  • 6Cohn JN,Levine TB,olivari MT,et al.Plasma norepine -phrine nore pinephmine as a guide to pnognosis in patients with congestive heart failure[J].Engl J Med,1984,311:819.
  • 7张明娟,吕卓人.抗高血压药物对左室肥厚的影响[J].中国医刊,2003,38(3):18-19. 被引量：5
  • 8许群.心力衰竭时血管扩张剂应用的原则与经验[J].中国实用内科杂志,1994,14(2):70-72. 被引量：24
  • 9Ader R,chatterjec K,Porto T,et al.Immediate and sustained hemodynamic and clinical improvement in chronic heart failure by an oral angiotensin converting enzyme inhibitor[J].Circulation,1980,61:931-934.
  • 10Cody RJ,Franklin KW,Kluger J,et al.Sympathetic responsiveness and plasma norepinephrine during therapy of chrohic congestive heart failure with captopril[J].Am J Med,1982,72:791.

二级参考文献8

  • 1[1]Van Zwieten PA. The influence of antihypertensive drug treatment on the prevention and regression of left ventricular hypertrophy. Cardiovasc Res,2000,45:82-91
  • 2[2]Van Zwieten PA. Centrally acting antihyprttensives: a renaissance of interest. Mechanisms and haemodynamics. J Hypertens, 1997,15 ( suppl. 1 ): S3- S8
  • 3[3]Castellano M, Bühm D.The cardiac β-adrenoceptor mediated signalling pathway and its alterations in hypertensive heart disease. Hypertension,1997,29:715 - 722
  • 4[4]Spinale FG,Holzgrefe H,Mukherjee R,et al. Angiotension-converting enzyme inhibition and angiotensin Ⅱ subtype-1 receptor blockade during the progression of left ventricular dysfunction. J Pharm Exp Ther, 1997,283:1082- 1094
  • 5[5]Schussheim AE, Diamond JA, Philips RA. Left ventricular midwall function improves with antihypertensive therapy and regression of left ventricular hypertrophy in patients with asymptomatie hypertension. Am J Cardio,2001,87:61 - 65
  • 6[6]Yu Guolong, Liang Xiaoqiu, Xie Xiumei, et al. Diverse effects of chronic treatment with losartan, fosinopril, abd amlodipine on apoptosis, angiotensin Ⅱ in the left ventricle of hypertensive rats. International J Cardiology,2001 ;81:123 - 129
  • 7[7]Cheung B. Increased left-ventricular mass after losartan treatment. Lancet,1997,349:1743 - 1744
  • 8[8]Fraccarollo D, Hu K, Galluppo P, et al. Chronic endothelin receptor blockade attenuates progressive ventricular dilation and improves cardiac function in rats with myocardial infarction. Circulation, 1997,96:3963 - 3973

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包头医学院学报
2007年 第3期

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