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桥脑中央髓鞘溶解症2例报告并文献复习 被引量:1

Central Pontine Myelinolysis:2 Case Report and Literature Review
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摘要 目的:探索桥脑中央髓鞘溶解症(central pontine myelinolysis,CPM)的临床特点,提高诊断率。方法:对2例CPM患者临床资料进行分析并复习文献。结果:CPM患者常表现为四肢瘫痪、假性球麻痹、精神症状及癫痫发作,易引起误诊误治。结论:尽管CPM少见,但其有典型临床表现及核磁共振特征,结合临床综合分析,诊断并不困难。 Objective:To investigate the clinical features of central pontine myelinolysis (CPM),and improve the accurance of diagnosis. Methods :The clinical manifestation of 2 cases of CPM was analyzed and the related literature was reviewed. Results:The patients with CPM often presented with tetraplegia, pseudobulber paralysis, psychiatric symp tom and epilepsy, it could be misdiagnosed and mistreatment. Conclusion:Although CPM is rare, there are some typical clinical manifestations and some manifestations on MRI, associating with clinic data, we can make the diagnosis of CPM.
出处 《中国误诊学杂志》 CAS 2007年第16期3700-3701,共2页 Chinese Journal of Misdiagnostics
关键词 髓鞘溶解 中心性脑桥/诊断 误诊 Myelinolysis,central pontine/diagnosis Diagnostic errors
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参考文献5

  • 1Adams RV,Victor M,Mancall ET.Central pontine myelinolysis:A hifherto undedcribed disease occurring in alcoholic and malnourishedpatient[J].Arch Neurol Psychiatry,1959,81:154-162.
  • 2Martin RJ.Central pontine and extrapontine myelinolysis:the osmotic demyelination syndromes[J].J Neurol Neurosurg Psychiatry,2004,75(Supple 3):iii22-28.
  • 3Ramaeker VT,Reul J,Kusenbach G,et al.Central pontine myelinolysis associated with acquireal folate depletion[J].Neuropediatries,1997,28(2):126-130.
  • 4Deluca GC,Nagy Z,Esiri MM,et al.Evidence for a role for apoptosis in central pontine myelinolysis[J].Acta Neuropathol(Berl),2002,103(6):590-598.
  • 5贺健安,肖波,熊舸.脑桥中央髓鞘溶解症(附9例分析)[J].中国现代医学杂志,2005,15(12):1905-1906. 被引量:3

二级参考文献8

  • 1FINSTERER J, ENGELMAYER E, TMKA E, et al. Immunoglobulins are effective in pontine myelinolysis[J]. Clin Neuropharamacol, 2000, 23(2): 110-113.
  • 2RAMAEKERS VT, REUL J, KUSENBACH G, et al. Central pontine myelinolysis associated with acquire al folate depletion [J].Neuropediatries, 1997,28(2): 126-130.
  • 3KARP, LAURENO R. Pontine and Extranontine myelinolysis: a neurologic disorder following rapid correction of hyponatremia [J].Medicine(Baltimore), 1993, 72(6): 359-373.
  • 4DELUCA GC, NAGY Z, ESIRI MM, et al. Evidence for a role for apoptosis in central pontine myelinolysis[J]. Acta Neuropathol (Berl), 2002, 103(6): 590-598.
  • 5KUMAR SK, MONE AP, GRAY LC, et al. Central pontine myelinolysis:delayed chemqes on neuroimaging[J]. J Neuroimaging,2000, 10(3): 169-172.
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  • 7SULLIVAN EV, PFEFFERBANM A. Magnetic resonance relaxometry reveals central pontine abnormalities in clinically asymptomatic alcoholic men[J]. Alcohol Clin Exp Res, 2001, 25(8):1206-1212.
  • 8CRAMER SC, STEGBAUER KC, SCHNEIDER A, et al. Decreased diffusion in central pontine myelinolysis[J]. AJNR Am J Neuroradrol, 2001, 22(8): 1476-1479.

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