摘要
目的了解四川省西昌市海洛凶成瘾者社区美沙酮维持治疗的保持情况及其影响因素。方法从2004年3月至2004年9月,在四川省西昌市社区美沙酮维持治疗门诊点调查首次参加社区美沙酮维持治疗的吸毒者206人,分析其本底的礼会人口学、社会家庭功能、吸毒行为、性行为和治疗剂量与维持治疗保持的关系。结果至2005年10月,206个研究对象社区美沙酮维持治疗的平均保持时间为(8.98±5.74)个月,维持治疗时间达半年和1年的保持率分别为58.7%和34.6%。在多因素 Cox 比例风险模型分析中,目前有工作(HR,0.60;95% XI,0.39~0.92)、过去1个月帮家人做家务的次数≥30次(HR,0.59;95% CI,0.42~0.82)和自愿成毒治疗次数≥3次(HR,0.65;95%CI,0.47~0.91)与维持治疗脱失发生的关系差异有统计学意义。结论应对关沙酮维持治疗参加者开展干预服务以提高维持治疗的保持率。
Objective To explore factors associated with retention in a community-based methadone maintenance treatment (MMT) among heroin addicts in Xichang of Sichuan province. Methods All 206 heroin addicts were first admitted to MMT community-based program between March to September 2004. Baseline data of patients characteristics, social function, drug using behaviors, sexual behaviors, dose of methadone and retention were collected. Results Up to Oct, 2005, all 206 patients contributed 8.98 ± 5.74 person-months of following-up. The retention rates were 58.7% after 6 months and 34. 6% after 12 months respectively. Cox proportional hazard regression model indicated that the employed (HR,0. 60; 95% CI,0. 39-0. 92), helping family to do housework in past 30 days more than once a day (HR,O. 59; 95% CI,O. 42-0. 82 ) and previous self-detoxification t〉 3 times ( HR, 0. 65 ; 95% CI, 0. 47-0. 91 ) were independently associated with retention. Conclusion We should give individual counseling to help heroin addicts increasing compliance.
出处
《中华预防医学杂志》
CAS
CSCD
北大核心
2007年第4期250-253,共4页
Chinese Journal of Preventive Medicine
基金
国家自然科学基金(30571612
10501052)
国家十五科技攻关资助项目(2004BA719A01
2004BA719A02)
卫生部艾滋病防治应用性研究资助项目(WA2003-13)
关键词
前瞻性研究
美沙酮
药物疗法
海洛因依赖
Prospective studies
Methadone
Drug therapy
Heroin dependence