摘要
目的评价普通体表心电图 T 波峰-末间期(Tpeak-Tend,Tp-e)作为 Brugada 综合征(Brs)一种新的危险分层指标。方法将23例男性 BrS 患者与20例男性阵发性室上性心动过速(PSVT)患者的体表心电图 Tp-e 值进行比较。结果 Tp-e 平均值,BrS 组为(109.57±22.86)ms,PSVT 组为(88.50±13.08)ms,两组间差异有统计学意义(P<0.05)。BrS 组中16例患者并发心脏事件(晕厥、临床记录心室颤动、电生理诱发心室颤动),7例患者无上述心脏事件,心脏事件组的 BrS 患者 Tp-e 值较无心脏事件组 BrS 患者和 PSVT 组患者显著延长(P<0.05),而无心脏事件组 BrS 患者与PSVT 组患者 Tp-e 值间差异无统计学意义(P>0.05)。结论 Tp-e 值延长(Tp-e≥120 ms)可作为BrS 患者一种新的无创性危险分层指标。
Objective To evaluate the possible association between Tpeak-Tend （Tp-e） interval in surface standard ECG and cardiac events in patients with Brugada syndrome （BrS）. Method Tp-e interval in surface standard ECG was compared between BrS patients （n = 23, all males ） and paroxysmal supraventricular tachycardia （PSVT） patients （n = 20, all males） as well as between BrS patients with （n = 16） or without （n = 7） cardiac events. Results There was significant difference in Tp-e interval between BrS patients and PSVT patients [ （ 109. 57 ± 22. 86） ms vs. （ 88.50 ± 13.08 ） ms, P 〈 0. 05 ]. Tp-e interval was also significantly longer in BrS patients with cardiac events （ syncope, clinical ventricular fibrillation and induced VF during electrophysiological study） than BrS patients without cardiac events [ （118.12 ± 20.40 ） ms vs. （90. 00 ± 15.27） ms, P 〈0. 05 ] while Tp-e interval was similar between BrS patients without cardiac events and PSVT patients （ P 〉 0. 05 ）. Conclusion The prolongation of Tp-e （ ≥ 120 ms） was associated with higher cardiac events in BrS patients.
出处
《中华心血管病杂志》
CAS
CSCD
北大核心
2007年第7期629-632,共4页
Chinese Journal of Cardiology
基金
国家自然科学基金(30570746)
南京医科大学创新基金(CX2003015)
