摘要
目的:比较经尿道前列腺等离子双极电切术(PKRP)与经尿道前列腺电切术(TURP)治疗BPH的临床疗效及安全性。方法:将164例BPH患者随机均分成PKRP组和TURP组,比较两组术后最大尿流率(Qmax)、剩余尿量(PVR)、国际前列腺症状评分(IPSS)、生活质量评分(QOL)等指标。结果:PKRP组72例、TURP组76例获得随访,随访时间3个月。PKRP组尿道外口狭窄2例,膀胱颈挛缩1例,TURP组尿道外口狭窄6例,膀胱颈挛缩4例;PKRP组Qmax为(22.6±4.6)ml/s,PVR为(8.6±4.4)ml,IPSS为(4.6±1.2)分,QOL为(1.2±0.6)分;TURP组分别为(24.2±4.2)ml/s、(9.6±3.6)ml、(4.4±1.0)分、(1.4±0.8)分,两组比较差异有统计学意义(P<0.05)。结论:PKRP与TURP治疗BPH疗效相近,但PKRP平均手术时间、术中出血量、围手术期及术后并发症较TURP明显减少,手术安全性高,有良好的应用前景。
Objective:To compare the clinical efficacy and safety of transurethral plasma kinetic resection of prostate (PKRP) and transurethral resection of prostate (TURP) for benign prostatic hyperplasia (BPH). Methods:Totally 164 BPH patients with matched lesions were divided into 2 groups: PKRP group and TURP group at our institute. The clinical date and therapeutic results were measured and compared between the 2 groups. Results: In PKRP group, the average operative time, intraoperative bleeding, the rates of postoperative temporary urinary incontinence(within 1 month), secondary hemorrhage (within 1 month) were (60 ± 16) min, (224 ± 78) ml, 17.1 %(14/82) and 9.8% (8/82), respectively; while in TURP group, these parameters were(80±21)min, ( 408± 115)ml, 31.7 % (26/82) and 18. 3% (15/82), respectively. Significant differences were found between the 2 groups ( P 〈0.05). Resected prostate weight was 28. 6 ±3.6 g in PKRP group versus 26.2 ±3.2g in TURP group. Intraoperative blood transfusion rate was 1.2 % (1/82) in PKRP group and 3.6 % (3/82) in TURP group. There were 3 pre-transurethral resection syndrome(TURS) patients and 1 TURS patient in TURP group, No transurethral resection syndrome(TURS) occurred in PKRP group. Of all the cases, 72 patients of PKRP and 76 patients of TURP were followed up for 3 months. Three patients in PKRP group and 10 patients in TURP group were found having urethral stricture after 3 months. In PKRP group, Qmax, postvoid residual(PVR) , the International Prostate Symptom Score(IPSS) and quality of life (QOL) were (22.6±4.6)ml/s, (8. 6±4.4)ml, (4.6 ±1.2) scores, (1.2±0.6) scores , respectively; while in TURP group,these parameters were (24.2±4.2)ml/ s, (9. 6±3. 6)ml, (4.4±1.0) scores, (1.4±.08) scores, respectively, these parameters were significantly improved after both procedures( P 〈0. 05), but there was no significant difference in the above parameters between 2 groups ( P 〉0. 05). Conclusions .. PKRP and TURP have'similar efficacy in the treatment of BPH, but PKRP is safer and less complicated than TURP. Thus, PKRP is a better treatment option for BPH.
出处
《临床泌尿外科杂志》
2007年第7期520-522,共3页
Journal of Clinical Urology
关键词
良性前列腺增生
经尿道前列腺等离子双极电切术
经尿道前列腺电切术
Benign prostatic hyperplasia
Transurethral resection of prostate
Transurethral plasmakinetic resection of prostate