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P300／CBP功能异常与白血病发生的关系研究进展

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摘要 乙酰转移酶根据其结构和活性可分为五个大家族：①PCAF／GNAT（GNS5、PCAF、ELP3、ATF2），与酵母HAT的GCN5高度相关；②P300／CBP，转录复合物的辅助激活因子；③TAFⅡp250，基本转录复合物TAFⅡE的重要组成部分；④SRC／ACTR，配体依赖的细胞核受体辅助激活因子；⑤MYSF（MOZ、MOF、YbF2／sas3、sas2、Tip60）。
作者 肖丽云 马旭东
机构地区 福建医科大学附属漳州市医院儿科 福建医科大学附属漳州市医院血液科
出处 《临床血液学杂志》 CAS 2007年第4期249-251,共3页 Journal of Clinical Hematology
关键词 乙酰化作用 组蛋白脱乙酰基酶 组蛋白类 白血病 白血病基因表达调控
分类号 R733.3 [医药卫生—肿瘤]
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参考文献15

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二级参考文献62

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共引文献8

临床血液学杂志
2007年 第4期

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