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糖尿病视网膜病变基础研究的热点和难点 被引量:17

Hotspots and problems of basic research for diabetic retinopathy
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摘要 糖尿病视网膜病变(DR)是糖尿病最常见的微血管并发症之一,其基础研究的重点主要包括病变视网膜的病理学观察、发病机制和药物对病变干预的观察。其发病机制研究中,以炎症一免疫机制、基因多态性为研究热点。单因素研究是现有研究中普遍存在的不足之处,开展多因素、多学科、多中心研究,才能促进研究工作向纵深发展,是将来DR基础研究的发展方向。 Diabetic retinopathy (DR) is one of the most common microvascular complications of diabetes mellitus, which is a leading cause of blindness. Nowadays basic research of DR mainly focuses on pathological observation of retina, pathogenesis and reaction of drugs intervention. Inflammatoryimmunologic mechanism and gene polymorphism are the hotspots. Due to the defect of single-factor study in research, we should carry out multi-factor study in DR research in future. In addition, we should strengthen the collaboration with other centers to improve the research of DR.
作者 李筱荣
出处 《中华眼底病杂志》 CAS CSCD 北大核心 2007年第4期234-237,共4页 Chinese Journal of Ocular Fundus Diseases
关键词 糖尿病视网膜病变/病因学 糖尿病视网膜病变/病理生理学 Dabetic retinopathy/etiology Dabetic retinopathy/pathophysiology
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参考文献24

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