摘要
Muller细胞是脊椎动物视网膜内最主要的神经胶质细胞。它贯穿整个视网膜,与视网膜神经细胞及视网膜血管发生多种功能的交互作用。糖尿病视网膜病变(diabetic retinopathy,DR)的发病机制至今尚未明,近年来的临床和基础研究发现DR患者和动物模型中Muller细胞超微结构和生理功能发生了变化,这种变化早于视网膜血管损伤。本文就近几年有关糖尿病视网膜Muller细胞形态结构及生理变化的研究进展作一综述。
Muller cells are the most principal neuroglial cells in vertabrate retina. They cross the entire thinckness of the retina and interact with neurocytes and retinal vessels. Considerable uncertainty remains about the exact nature of the insult that initiates diabetic retinal changes, but the overwhelming majority of evidence from studies of human diabetes and animal models pointed to the uhrastructural and physiological changes in advance of the dectectable retinal vascular changes. In this paper the current research of morphological structure and physiological changes of Muller cells in diabetic retinopathy were reviewed.
出处
《中国体视学与图像分析》
2007年第2期152-155,共4页
Chinese Journal of Stereology and Image Analysis
