摘要
目的:探讨辅助生殖技术(ART)受孕双胎妊娠与自然受孕双胎妊娠围生期的结局。方法:回顾分析93例ART受孕双胎妊娠孕妇(研究组)的并发症、分娩方式及围产儿结局,并与同期自然受孕双胎(对照组)451例比较。结果:研究组孕妇平均年龄较高(32.5±3.6岁),分娩孕周较小(33.4±4.3周),住院时间较长(21.1±2.6天),与对照组相比(分别为27.8±3.2岁、35.6±4.1周、11.3±1.5天)差异有显著性(P<0.05)。研究组早产、妊娠期高血压疾病、胎膜早破、前置胎盘、羊水过多的发生率明显高于对照组,两者差异有显著性(P<0.05)。研究组双胎输血综合征明显少于对照组(P<0.01)。两组剖宫产率均在72%以上,差异无统计学意义。研究组新生儿出生体重低、新生儿畸形和新生儿转NICU率高,与对照组相比有统计学差异(P<0.05)。研究组双胎之一胎死宫内率低于对照组(P<0.01)。结论:ART受孕双胎并发症和不良新生儿结局风险大,加强ART受孕双胎妊娠并发症的防治和产前、产时监护,产儿科密切合作和新生儿护理具有重要意义。
Objective： To compare the pregnancy outcome of twin pregnancies con-eeived by assisted reproductive technique （ART） and those conceived spontaneously. Methods：Tbe complieatoins, mode of delivery and pregnancy outcome of 93 twin pregnancies conceived by ART（ study group） and 451 spontaneous twin pregnacies （control group） were analyzed retrospectivdy. Results： Older mean age, shorter gestational weeks and longer hospital stay were found in the study group than those in the control group （ 32.5 ± 3.6 vs 27.8 ± 3.2 years old, 33.4 ± 4.3 vs 35.6 ± 4.1 gestational weeks,21.1 ± 2.6 vs 11.3± 1.5 days）. The difference between the two groups were significant（ P 〈0.05 ）. Higher incidence of premature deliv- , premature rupture of membrane, placenta previa, polyhydramnios and lower incidence of twintwin transfusion syndrome were found in the study group than those in the control group （P 〈 0.05 ）. Rate of cesarean delivery was above 72% in both two groups and no difference between them. Significantly higher incidence of lower birth weight, malformarion and admission to the neonatal intensive care unit was seen in the study group than those in the control group （ P 〈 0.05 ）. The incidence of one fetus intrauterine demise was lower in the study group than that in the control group （P 〈0.01 ）. Conclusion： When compared with sponteneous twin pregnancies, those conceived by ART are more likely to have complications and worse neonatal outcome. It is important to have a close monitoring during antepartum and intrapartum period, strengthen the coopertation between obstetrist and neonatologist, so as to have a better pregnancy outcome of twin pregnancy conceived by ART.
出处
《现代妇产科进展》
CSCD
北大核心
2007年第6期417-419,424,共4页
Progress in Obstetrics and Gynecology
关键词
双胎
生殖技术
辅助
妊娠结局
Twin pregnancy
Assisted reproductive technique
Pregnancy outcome
