摘要
目的探讨凝血功能异常在老年缺血性脑血管病中的临床意义。方法测定老年缺血性脑血管病患者血浆纤维蛋白原(Fbg)、D-二聚体(D-Dimer,DD)、抗凝血酶-Ⅲ抗原(AT-Ⅲ:Ag)和抗凝血酶-III活性(AT-Ⅲ:C)的水平变化。结果缺血性心脑血管病患者急性期血浆Fbg和DD水平明显升高,AT-Ⅲ:Ag和AT-Ⅲ:C明显降低;稳定期Fbg和DD水平较急性期组明显降低,AT-Ⅲ:Ag和AT-Ⅲ:C较急性期组明显升高,但与正常组相比仍有显著差异。结论凝血功能异常可能是老年缺血性心脑血管病发生的主要危险因素之一,动态监测凝血功能对老年缺血性心脑血管病的预防和治疗有一定意义。
Objective To analyze the significance of changes of blood coagulation disorder in elderly patients with ischernic cerebrovasecular disease. Methods The levels of Fbg, D - Dimer, AT- Ⅲ ： Ag and AT -Ⅲ ： C in elderly patients with ischemic cerebrovaseMar disease and normal subjects were detected. Results The levels of Fbg and D - Dimer were significantly higher, AT - Ⅲ： Ag and AT - Ⅲ ： C in elderly patients with ischemic cerebrovascular disease were singiflcandy lower than that of normal subjects in acute episode. In stationary phases, the levels of Fbg and D - Dimer were significantly lower, AT - Ⅲ ： Ag and AT- Ⅲ - C of elderly patients with ischemic cerebrovaseular disease were singSficandy higher than that of in acute stage. Conclusion The blood coagulation disorder may be risk factor lot ischemic cerebrovaseular disease in the elderly, The monitoring of coagulation function in he elderly may be helpful for prevention and treatrnem of ischernic cerebrovascular disease in he elderly.
出处
《中国热带医学》
CAS
2007年第8期1360-1361,共2页
China Tropical Medicine
