摘要
目的对比分析体外循环阻断与不阻断冠脉循环瓣膜置换术的临床效果。方法182例患者分为阻断冠脉循环组(83例)和不阻断冠脉循环组(99例)。术前两组一般临床资料均衡。不阻断组采取不阻断升主动脉顺灌或阻断升主动脉从冠状静脉窦逆灌,保持心肌氧合血的持续灌注,在心脏停跳或不停跳下实施瓣膜置换术。术后比较两组呼吸、循环相关指标及各心血管活性药物用量。结果不阻断组术后多巴胺、多巴酚丁胺、西地兰用量及机械辅助呼吸时间均小于阻断组(P<0.05)。结论体外循环不阻断冠脉循环瓣膜置换术有更好的心、肺保护效果。
Objective To compare the clinical outcomes of cardiopulmonary bypass （CPB） valve replacements with coronary circulation arrest or non-arrest, Methods Of 182 patients,83 received valve replacements with coronary circulation arrest, while 99 without coronary circulation arrest, There were no significant differences of the preoperative clinical date between the two groups. In the non-arrest group, ascending aorta were not clamped, or clamped with coronary artery retrograde perfused from the vena coronary vein sinus, in order to maintain the blood supply to the myocardium, The postoperative data of breath, circulation, dosage of inotropes in two groups were collected and compared, Results In the non-arrest group, dosage of inotropes, and assisted respiration time were significantly less than that in arrest group （P〈0.05）. Conclusion The outcomes of valve replacements with no coronary circulation arrest were superior to that of with coronary circulation arrest.
出处
《中国现代医药杂志》
2007年第7期1-5,共5页
Modern Medicine Journal of China
关键词
体外循环
冠状动脉循环
瓣膜置换手术
不阻断
Cardiopulmonary bypass （CPB） Coronary circulation Valve replacement Non-arrest
