摘要
甘精胰岛素和地特胰岛素是2种新型的人胰岛素类似物。虽然他们都通过基因工程的方法生产,药效能持续24h,无明显的波峰和波谷,是真正意义上的基础胰岛素,但是这2种长效胰岛素的分子结构、长效机制、生产工艺各不相同,在临床使用上也有各自的利弊。
Insulin glargine and insulin detemir are both of human insulin analogs, produced through genetic research engineering. They are both basal insulins; because of they can remaining active for a full 24 hours with essentially no peaks or valleys, but having different molecular structure, long acting mechanisms, artworks and different clinical effects.
出处
《中国新药与临床杂志》
CAS
CSCD
北大核心
2007年第7期548-552,共5页
Chinese Journal of New Drugs and Clinical Remedies
关键词
甘精胰岛素
地特胰岛素
糖尿病
insulin glargine
insulin detemir
diabetes mellitus
