摘要
目的探讨血浆致动脉粥样硬化指数(AIP)与2型糖尿病(T2DM)患者合并冠心病的关系。方法选择96例2型糖尿病患者,按有无合并冠心病分成两组,测量身高、体重,计算体重指数(BMI),测量血压、血脂,血糖,计算AIP(指TG/HDL-C比值的对数值)。结果与2型糖尿病组比较,合并冠心病组BMI、TG、TC、HDL-C、LDL-C差异无显著性(P>O.05),而AIP值差异显著(P<0.001),多因素logistic回归分析显示AIP与糖尿病合并冠心病的发生呈独立正相关关系(P<0.01)。结论AIP间接反映LDL-C颗粒直径的大小,可作为2型糖尿病患者发生大血管并发症危险性独立指标。
Aim To investigate the relationship between atherogenic index of plasma and type 2 diabetes with coronary heart disease（CHD）.Methods 96 type 2 diabetic patients were divided into two groups based on with or without coronary heart disease.Atherogenic index was defined as the Log value of TG/HDL-C ratio.Results There were no significant difference between two groups on the value of BMI,TG,TC,LDI-C（P〉0.05）,but the value of AIP in patients with complicated coronary heart disease were significantly higher than those without complications（P〈0.001）.Multivariate logistic regression analysis shows that AIP was positive correlation to CHD in the patients with type 2 patients.Conclusion The value of AIP can be regarded as an independent risk marker for the type 2 diabetes with CHD.
出处
《安徽医药》
CAS
2007年第8期733-734,共2页
Anhui Medical and Pharmaceutical Journal
