摘要
目的评价肝癌的局部根治性切除术结合骨髓间充质干细胞输注对原发性肝癌(PHC)的疗效。方法取符合手术适应证的肝癌患者40例,随机分成治疗组(30例)及对照组(10例),均采用局部根治性切除术,术后治疗组注射骨髓间充质干细胞(1.8×106/kg),观察疗效及生存率。结果治疗后1年、2年的肿瘤局部有效率分别为90%、60%。1～2年生存率分别为90%、30%,中位生存期21个月。结论局部根治性切除术结合骨髓间充质干细胞输注是治疗PHC的有效治疗手段。
Objective To investigate the results of local radical excision plus perfusion of MSC for primary hepatic carcinoma （ PHC）. Meth- ods 40 patients with PHC were randomly assigned to receive perfusion of MSC after radical local radical excision （ n = 30 ） or to receive local radical excision only （n = 10）. Therapeutic results and survival rate were compared between the two groups. Results One year after treatment, the local response rate was 90% and 60% , respectively. 1 - 2 year survival rate was 90% and 30%, respectively. The median survival period was 21 months. Conclusion Local radical excision plus perfusion of MSC is an effective therapy for PHC.
出处
《临床和实验医学杂志》
2007年第9期17-18,共2页
Journal of Clinical and Experimental Medicine
