摘要
目的 探讨起病于婴幼儿期的结节性硬化症病人的发病特点。方法 采用回顾性调查和追踪观察的方法，分析16例起病于婴幼儿期结节性硬化症患儿的临床资料。结果 16例结节性硬化症的儿童发病年龄为～3岁，均以癫痫为首发症状（100％，16／16），主要发作类为婴儿痉挛、复杂部分性发作，并有患儿从部分发作继发全身强直-阵挛发作；智力低下11例（69％，11／16），皮肤损害5例（31％，5／16）。全部患儿均有头部CT或MRI改变。结论 结节性硬化症以婴儿痉挛为主要发作形式的患儿脑损害显著；脑损害程度与癫痫发作频率有关；智力低下伴有语言／言语缺陷。
Objective To explore the characteristic of Tuberous Sclerosis brought from infancy. Methods A retruspective method was adopted to study the clinical data of 16 Tuberous Sclerosis from infancy. Results The children in 16 Tuberous Sclerosis from infancy, are three years old, the first symptom is from epilepsy, the mostly outbreak are infant hyperkinesias, complex portion outbreak, and some children have baby strive- hyperkinesia; have 11 mental subnormality（69%, 11/16）, 5 damages in skin（31% ,5/16）. All sick ehildren have some changes in brain through CT OR MRI. Conclusions; Tuberous Selerosis is a disease whose form is mostly infant hyperkinesias and brain damage. Intelligence move back have some links with out- break frequency in clinic. The characteristics of Intelligence obstruction are memory fade and talk obstacle.
出处
《中国病案》
2007年第8期F0004-F0004,45,共2页
Chinese Medical Record
关键词
结节性硬化症
婴幼儿
智力低下
Tuberous Sclerosis
infant
Intelligence lowlihead
