期刊文献+

抑癌基因与乳腺癌的研究进展 被引量:2

Progress in research of antioncogenes of breast cancer
下载PDF
导出
摘要 乳腺癌的发生、发展是多种遗传学改变的结果,涉及到多种基因的异常,其中包括多种抑癌基因,这些基因在乳腺癌的发生、发展过程中起着重要作用。通过研究和识别这些抑癌基因,对乳腺癌的早期诊断、预后评价以及基因治疗具有重要意义。 The occurrence and development of breast cancer in-volves many kinds of genetic changes, and there are many gene vari-ations in the whole course including many antioncogenes. These an- tioncogenes play an important role in the course of occurrence and development of breast cancer. Investigation and verification of these antioncogenes lie specially significance in early diagnosis, prognosis evaluation and gene treatment of breast cancer.
出处 《中华肿瘤防治杂志》 CAS 2007年第17期1350-1353,1359,共5页 Chinese Journal of Cancer Prevention and Treatment
关键词 乳腺肿瘤 易感基因 抑癌基因 综述文献 breast neoplasms susceptibility gene antioncogene review literature
  • 相关文献

参考文献6

二级参考文献52

  • 1南克俊,魏永长,李春丽,隋晨光,阮之平,黄辰.肝癌患者血清p16甲基化检测[J].中华肿瘤杂志,2004,26(9):569-570. 被引量:2
  • 2王英超,付士波,张虹,韩猛,石爱平,王有德.乳腺成体干细胞的体外分离、培养及鉴定[J].吉林大学学报(医学版),2005,31(2):314-316. 被引量:2
  • 3宋传贵,胡震,袁文涛,狄根红,沈镇宙,黄薇,邵志敏.中国上海家族性乳腺癌BRCA1和BRCA2基因的突变[J].中华医学遗传学杂志,2006,23(1):27-31. 被引量:29
  • 4Steeg PS, Bevilacgua G, Kopper L, et al. Evidence for a novel gene associated with low tumor metastatic potential[J] .J Natl Cancer Inst,1988,80(3):200.
  • 5Hennessy C, Henry JA, May FE,et al. Expression of the antimetastatic geng nm23 in human breast cancer:An association with good prognosis[J]. J Natl Cancer Lust,1991,83(4) :281.
  • 6Michael PD. Clinical significance of HER-2/neu overexpression : Part I [M]. Principles & Practice of Oncology,1999,13(1) :1.
  • 7Velculescu VE, EL-Deity WS. Biological and clinical importance of the p53 tumor suppressor gene [J]. Clin Chem, 1996,42(6) :858.
  • 8Marx J. Cell death studies yiecd cancer clues[J]. Science, 1993, 259:760.
  • 9Sobel MEE.Metastasis suppressor genes[J].J Natl Cancer,1990,82:267.
  • 10Korsmeyer SJ. bcl-2 Initiates a new category of oncogenes: Regulators of Cell death[J]. Blood,1992,80(4):879.

共引文献40

同被引文献33

  • 1马捷,孙国平.p53基因与乳腺癌的相关性[J].医学综述,2005,11(2):112-113. 被引量:6
  • 2鲍炜,裘秀春,贾林涛,张立红,王成济,杨安钢.HER2分子与肿瘤靶向治疗[J].医学分子生物学杂志,2006,3(2):129-132. 被引量:17
  • 3Hayes D F, Yamauchi H, Broadwater G, et al. Circulating HER-2/ erbB-2/c-neu (HER2) extracellular domain as a prognostic factor in patients with metastatic breast cancer: Cancer and Leukemia Group B study 8662[J]. Clin Cancer Res,2001,7(9) :2703-2711.
  • 4Garcia caballero T, Menende Z M D, Vazque z Boquete A,et al. HER-2 status determination in breast carcinomas. A practical approach[J]. Histol Histopathol,2006,21(3) :227- 236.
  • 5Lal P, Tan L K,Chen B. Correlation of HER-2 status with estrogen and progesterone receptors and histologie features in 3 655 invasive breast careinomas[J]. Am J Clin Pathol, 2005 123<4) :541- 546.
  • 6Rastelli F, Crispino S. Factors predictive of response to hormone therapy in breast cancer[J]. Tumori,2008,94(3):370-383.
  • 7Lee K H,Im S A,Oh D Y,et al. Prognostic significance of bcl-2 expression in stage Ⅲ breast cancer patients who had received doxorubicin and cyclophosphamide followed by paclitaxel as adjuvant chemotherapy[J]. BMC Cancer, 2007,7 : 63.
  • 8Bieche I, Onody P, Tozhu S, et al. Prognostic valur of ERBB family mRNA expression in breast carcinomas[J]. Int J Cancer, 2003,106(5) :758-765.
  • 9Irvin W J Jr, Carev L A. What is triple-negative breast cancer? [J]. Eur J Cancer, 2008,44(18) :2799-2805.
  • 10Solbach C, Roller M, Budischewski K, et al. EGF-R and HER2/ neu overexpressing tumors: independent collectives for treatment of breast cancer by specific monoclonal antibody-therapy[J]. J Cancer Res Clin Oneol,2003,129(4) :250- 251.

引证文献2

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部