摘要
采用高效液相色谱法测定替尼泊甙注射液含量,替尼泊在0.05~5μl/10μl浓度范围内线性良好,r=0.9999。方法回收率为100.82,RSD<0.95%。方法简便、准确、灵敏。
Determination of a new antineoplastic agent, teniposide by HPLC was developed in this paper. The method consists of a RP--C(18)column (4. 6×220mm id) with methanol-water (60:40) as the mobile phase at a now rate of 1. 0ml/min. spectrophotometric detection was at 254nm.method was simple,acurate and sensitive. The calibration curve was liner in the concentration range of 0. 05~5μg/10μl. RSD was lower than 0. 95 %,mean recovery was 100. 82% (n=18). The assay of teniposide injections were developed.
出处
《华西药学杂志》
CAS
CSCD
北大核心
1997年第2期117-118,共2页
West China Journal of Pharmaceutical Sciences