摘要
采用小鼠腹腔注射乙酸铅溶液10d,建立染铅小鼠模型,连续15d灌胃给予苹果多酚,研究苹果多酚的促排铅作用。石墨炉原子吸收法测试血铅、尿铅、粪铅和股骨、肝脏中铅含量。结果表明:染毒小鼠给予苹果多酚后,血铅和股骨、肝脏中铅含量明显低于阳性对照组,而尿铅明显高于阳性对照组。苹果多酚具有明显的促排铅效果。
The purpose of this paper was to evaluate the lead discharging effects of apple polyphenol (AP) on male Kunming mice given lead. Lead acetate was administered by intraperitoneal injection for 10 days. Administration of AP to mice by gastric incubation was performed for 15 days from the end of lead exposure up to the end of the experiment. Then, the mice were sacrificed for comparison of lead distribution. Concentrations of lead in the specimens were determinated by graphite furnace atomic absorption spectrophotometry. It was observed that the blood lead, the liver lead and the femur level significantly decreased, but urinates lead elimination significantly increased. The results illustrated that AP could discharge lead.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2007年第8期468-470,共3页
Food Science
关键词
铅中毒
苹果多酚
排铅
lead poisoning
apple polyphenol
lead discharging