摘要
13-顺维甲酸与溴代-2,3,4,6-四-O-乙酰基-α-D-吡喃葡萄糖在4-二甲氨基吡啶催化下合成了13-顺维甲酸葡萄糖酯(5),以二氧化锰为氧化剂,5经氧化成功地合成了新化合物13-顺-4-羰基维甲酸葡萄糖酯(6)。5和6的结构经1H NMR,13C NMR,IR和MS表征,结果表明5和6均为β-构型糖酯。
Glycosyl ester of 13-c/s-4-oxo-retinoic acid（6） was successively synthesized first by the reaction of 13-cis-retinoic acid with 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide in the presence of 4-dimethylaminopyridine and then by oxidation using manganese dioxide as an oxidant. Structures of glycosyl ester of 13-c/s-4-restinoic acid（5） and fi were characterized by ^1H NMR,^13C NMR, IR and MS and confirmed to be β-configuration.
出处
《合成化学》
CAS
CSCD
2007年第4期459-462,共4页
Chinese Journal of Synthetic Chemistry
基金
安徽理工大学青年教师研究基金资助课题
