摘要
目的观察地尔硫卓对气管插管应激反应的防治效果。方法选择全麻病人60例,随机分为例数相等的A组和对照(B)组。A组在全麻诱导插管前静注地尔硫卓0.02 mg/kg;B组在诱导及插管前静注生理盐水10 ml。随后观察术前、插管即刻,插管后10 min 3个时段的收缩压(SBP)、舒张压(DBP)及心率(HR)。结果B组在插管即刻及插管后10min的SBP、DBP、HR均较术前明显升高,A组在插管即刻及插管后10 min有轻微变化;B组在插管即刻及插管后10 min的各项指标均高于A组。结论地尔硫卓可以有效防治气管插管时的应激反应。
Objective To observe the protective effect of dilthiazem on stress reaction of tracheal intubation. Methods 60 patients who scheduled to undergo general anesthesia were divided into dilthiazem group （group A） and control group （group B） randomly. Group A was given dilthiazem of 0. 02g· kg^-1 before intubation while group B given sodium chloride 10ml. Systolic blood pressure （SBP）, diastolic blood pressure （DBP） and heart rate （HR） were observed before, instant, and 10 min after intubation. Results As compared with preintubation, DBP and HR increased significantly at the immediate moment of intubation and 10 min after intubation in group B （P〈0.05）, while there were no significant changes in group A. SBP, DBP and HR were higher in group B than A（P〈0. 05）. Conclusion The result suggests that dilthiazem can prevent stress reaction of tracheal intubation.
出处
《西部医学》
2007年第5期879-879,881,共2页
Medical Journal of West China
