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滤过手术中加用高浓度5-氟尿嘧啶 被引量:1

Filtering operation supplement by intraoperative 5-fluorouracil in high concentration
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摘要 各类青光眼33例45眼,其中包括曾经手术失败,葡萄膜炎继发青光眼,新生血管性青光眼及青少年青光眼等。具有失败高危因素12例18眼。以穹隆部为基底的结膜瓣,在术中利用25mg/ml的5一氟尿嘧啶(5-Fu)敷贴5分钟,术后只在结膜下注射该药4次,术后随访(平均6.5月)复查41眼(91.1%),眼压≤2.79kPa(1kPa=7.5mmHg),有4眼发生角膜上皮缺损,1眼发生黄斑出血,1眼发生短暂前房积血。表明此种术中与术后使用5-Fu相结合的方法可适用于青光眼滤过手术。 33 cases(45 eyes)of various types of glaucoma, including 12 cases (18 eyes)with high risk of failure were operated with fornix-based conjunctival flap and intraoperative application of 5-fluorouracil 25mg/ml for 5-Fu was reduced to 4 the.,Follow-up at average 6. 5 months after operation showed the intraocular pressure was kept≤2.79kPa in 41 eyes (91. 1% ).As to the relatal complications, there occurred only corneal staining with fluorescein in 4 eyes, macular hemorrhage in 1 eye,and a transient hyphema in 1 eye. The strategy of combined intraopetiove and postoperative use of 5-Fu seemed quite advisible in filtering surgery.
出处 《眼外伤职业眼病杂志》 北大核心 1997年第2期100-101,共2页 Journal of Injuries and Occupational Diseases of the Eye with Ophthalmic Surgeries
关键词 青光眼 小梁切除术 5-氟尿嘧啶 Glaucoma Trabeculectomy 5-Fu
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