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沙参、砂仁、猪苓、莪术和鸡血藤对环磷酰胺毒副反应影响的实验研究 被引量:12

EXPEREMENTAL STUDY ON FIVE KINDS OF CHINESE MEDICINES REDUCING TOXICITY BY CYCLOP HOSPHOMIDUM
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摘要 本文以5味中药沙参、砂仁、猪苓、莪术和鸡血藤为研究对象,以小鼠为实验动物,检测其对肿瘤化疗常用药环磷酰胺所产生毒副反应的减轻作用。实验结果表明:此5味中药对环磷酰胺引起的骨髓嗜多染红细胞(PCE)微核率(MNR)的聚增以及外周血白细胞值红细胞值和血红蛋白值的降低均有显著的抑制或缓解功效,提示其在肿瘤辅助治疗中具有开发价值和应用前景。 This experiment used micronucleus rate(MNR), leukocyte (WBC) , erythrocyte CRRC) and hematoglobin(Hb) of mice as markers, tested thestraight ladybell(Adenophora stricta) ?interiore-ardamon (Amamum villosum) , umbellate pore fungus (Ployporus umbellata) , ezhu (Curcuma zc-doaria) and reticulate millettia (Millettia reticulata) reducing toxicity of cyclophosphomidum (CPA). The results showed that the Skinds of Chinese medicines could restrain rising of MNR arid falling of WBC amount, RBC amount and Hb amount by CPA. These Suggested that the five kinds Chinese herbs was worth developing and applying in the auxiliary treatment of cancer.
出处 《中国中医药科技》 CAS 1997年第3期153-154,175,共3页 Chinese Journal of Traditional Medical Science and Technology
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  • 1北京大学生物系遗传学教研室.遗传学实验方法和技术[M]高等教育出版社,1983.

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