摘要
目的探讨多发性硬化中发作性症状的发生率、临床特点、发病机制和治疗。方法对我院18年来100例多发性硬化住院患者进行回顾性分析,对具有发作性症状的MS患者根据其临床特点分类,分析影像学、电生理特点,总结其异同点。结果多发性硬化中发作性症状的发生率27%,临床表现不一,其中以痛性强直发作占37.0%、Lhermitte症占44.4%、发作性感觉异常占44.4%、癫痫占37.0%最为常见,其发病机制近似相同。结论MS发作症状共同点:突发突止,刻板重复,历时短暂;予抗癫痫药治疗有效。
Objective To explore the incidence rate, the clinical features, pathogenesis and treatment of paroxysmal symptoms in multiple sclerosis（MS）. Methods We retrospectively analyzed 100 inpatients with MS for 18 years and studied the clinical manifestations, imaging findings and electrophysiology of patients with paroxysmal symptoms in multiple sclerosis. Results 27% patients may be seen the paroxysmal symptoms in MS, include ataxia and dysarthria, trigeminal neuralgia（44.4 %）, tonic seizures （37.0%）, vertigo, epilepsy（37.0%）, painful paresthesias（44.4%） and akinesia, and which seem to show the similar pathogenesis. Conclusions The attacks were flup, stereotyped and short- time. The mechanisms are not known, and anti--epileptic drugs treatment shows effective.
出处
《神经疾病与精神卫生》
2007年第2期95-97,共3页
Journal of Neuroscience and Mental Health
基金
江苏省卫生厅重大课题H200302资助
