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短时间大剂量糖皮质激素对有复发迹象的系统性红斑狼疮患者的疗效观察 被引量:4

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摘要 目的探讨短时间大剂量糖皮质激素对有复发迹象的系统性红斑狼疮患者的治疗效果。方法选择在糖皮质激素减量治疗过程当中且近期出现了白细胞下降、血小板或补体降低的31例系统性红斑狼疮患者,给予7d大剂量糖皮质激素治疗,然后恢复到原来的治疗剂量,2周后观察下降的异常指标。结果64.1%的患者异常指标能完全恢复正常,另有19.3%的患者有明显好转,只有16.2%的患者无效。结论对有复发迹象的系统性红斑狼疮患者,短时间给予大剂量糖皮质激素治疗在短期内能取得良好的治疗效果,既不过度治疗,又有效地避免了长期使用大剂量糖皮质激素带来的不良反应。
出处 《四川医学》 CAS 2007年第8期864-865,共2页 Sichuan Medical Journal
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  • 1Petri M,Genovese M,Engle E,et al.Definition,incidence,and clinical description of flare in systemic lupus erythmatosus:a prospective cohort study[J].Arthritis Rheum,1991,34(8):937 - 944.

同被引文献35

  • 1贺振泉,张进,陈文华,王家有,汤建华,唐雷.脐疗机制新解—经络筋膜说[J].实用医学杂志,2005,21(18):2099-2100. 被引量:92
  • 2顾越英,叶霜.糖皮质激素在系统性红斑狼疮中的应用[J].中华全科医师杂志,2006,5(4):199-202. 被引量:8
  • 3王烈,杨小湜,侯哲,冯巧莲,丸井英二.护理者负担量表中文版的应用与评价[J].中国公共卫生,2006,22(8):970-972. 被引量:573
  • 4吴东,石娜,朱崇田,黄泳,朱忠春(译).Treatment of Sleep Deprivation-induced Circadian Rhythm Disorder by Applying Garlic Cream on Acupoint Shenque (CV 8)[J].Journal of Acupuncture and Tuina Science,2007,5(3):142-146. 被引量:1
  • 5Barath S,Soltesz P,Kiss E,et al.The severity of systemic lupus erythematosus negatively correlates with the increasing number of CD4+CD25(high) FoxP3+regulatory T cells during repeated plasmapheresis treatments of patients[J].Autoimmunity,2007,40:521-528.
  • 6Nikolov NP,Pavletic SZ.Technology Insight:hematopoietic stem cell transplantation for systemic rheumatic disease[J].Nat Clin Pract Rheumatol,2008,4:184-191.
  • 7Alexander T,Andreas T,Oliver R,et al.Depletion of autoreactive immunologic memory followed by autologous hematopoietic stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system[J].Blood,2009,113:214-223.
  • 8Gunnarsson I,Sundelin B,Jonsdottir T,et al.Histopatholoic and clinical outcome of rituximab treatment in patients with cyclophosphamide-resistant proliferative lupus nephritis[J].Arthrits Rheum,2007,56(4):1263-1272.
  • 9Boumpas DT,Furie R,Manzi S,et al.A short course of BG9588(anti-CD40 ligand antibody) improves serologicactivity and decreases hematuria in patients with proliferative lupus glomerulonephritis[J].Arthritis Rheum,2003,48:7l9.
  • 10Usmani N,Goodfield M.Efalizumab in the treatment of discoid lupus erythematosus[J].Arch Dermatol,2007,143(7):873.

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