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1,3-偶极环加成合成双-4,5-二氢-1,2,4-噁二唑啉衍生物 被引量：2

Synthesis of Bis-4,5-dihydro-1,2,4-oxadiazoline Derivatives by 1,3-Diplor Cycloaddition
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摘要 用2-苯基-1,2,3-三唑基-4-甲醛(1)或喹喔啉基-2-甲醛(2)与乙二胺缩合成双席夫碱3或4,然后与α-氯代肟在三乙胺条件下发生1,3-偶极环加成得到双-4,5-二氢-1,2,4-噁二唑啉衍生物6a～6f或7a～7f.目标化合物的结构经元素分析,IR,1HN MR和MS确认. Condensation of ethylenediamine with 2-phenyl- 1,2,3-triazole-4-carboxaldehyde （1） or quinoxa- line-2-carboxaldehyde （2） gave bis-Schiff base 3 or 4, which then reacted with a-chloro-oximes to afford bis- bis-4,5-dihydro-1,2,4-oxadiazoline derivatives 6a-6f or 7a-7f by 1,3-dipolar cycloaddition. The structures of new compounds were confirmed by elemental analysis, IR, ^1H NMR and MS spectra.
作者 胡君 解正峰 惠永海 貊雪霞 孙翔 刘方明
机构地区 新疆大学化学化工学院 中国石油塔里木油田塔石化分公司
出处 《有机化学》 SCIE CAS CSCD 北大核心 2007年第9期1162-1166,共5页 Chinese Journal of Organic Chemistry
基金 国家自然科学基金(No20562011) 新疆大学青年启动基金资助项目
关键词 喹喔啉-2-甲醛 2-苯基-1 2 3-三唑基-4-甲醛 双席夫碱 1 3-偶极环加成 双-4 5-二氢-1 2 4-噁二唑啉衍生物 qinoxaline-2-carboxaldehyhyde 2-phenyl-1,2,3-triazole-4-carboxaldehyde bis-Schiff base 1,3-dipolar cycloaddition bis-4,5-dihydro- 1,2,4-oxadiazoline derivative
分类号 O626 [理学—有机化学]
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有机化学
2007年 第9期

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