摘要
四氯化碳体外损伤原代培养大鼠肝细胞的［３Ｈ］胸腺嘧啶核苷掺入量显著降低，培养液中ＡＬＴ活性显著增高；丹参酸乙（ＳＡ－Ｂ）能有效地阻抑细胞的这种病理变化，均以１０－６ｍｏｌ／Ｌ浓度的ＳＡ－Ｂ的作用最佳。
The incorporation of thymidine obviously tends to decrease in the primary cultured hepatocytes of rats when the cells are treated with carbon tetrachloride. Meanwhile the activity of ALT markedly increases in the medium. But these pathologic alterations are inhibited by Salvianic acid B(SA B)and the effect of 10 -6 mol/L SA B is the best.
出处
《中国中药杂志》
CAS
CSCD
北大核心
1997年第5期303-305,共3页
China Journal of Chinese Materia Medica
基金
国家自然科学基金
关键词
丹参
丹参酸乙
肝细胞损伤
Salvia miltiorrhiza
salvianic acid B
injured hepatocytes
