摘要
目的观察地塞米松联合吲哚美辛栓剂序贯用药防治肝豆状核变性合并脾功能亢进(脾亢)病人术后发热的疗效及并发症。方法分析1995年1月至2007年1月,小剂量地塞米松联合吲哚美辛栓剂序贯用药,防治45例肝豆状核变性病人脾切除术后发热,并与对照组42例进行比较。结果治疗组术后1周内体温恢复正常者42例(93.3%),术后2周内体温全部恢复正常(100%),发生各种并发症5例(11.1%);对照组术后1周内体温恢复正常者26例(61.9%),术后2周内共32例(76.2%),发生各种并发症12例(28.6%)。结论肝豆脾切除术后序贯应用地塞米松及吲哚美辛栓剂防治发热疗效确切(P<0.01)且能显著降低术后并发症(P<0.01)。
Objective To observe curative effect of sequential application dexamethasone and indomethacin suppository toe prevent fever and complications after splenectomy for wilson＇s disease complicated with hypersplenism. Methods To analyze treatment effect of application fine dose dexamethasone and indomethacin suppository to prevent fever after splenectomy for 45 patients with Wilson＇s disease, compared with 42 cases control group form January 1995 to January 2007. Results After splenectomy, among the therapy group 42 patients＇（93.3% ） temperature recovered the normal in one week;45 cases＇（ 100% ） in two weeks and various complications occurred in 5 cases（11.1% ）. In the control group,26 cases＇（61.9% ） temperatue recovered thenormal in one week（P 〈0.01） ; 32 cases＇s （76. 2% ） in two weeks （ P 〈 0. 01 ） and complications in 12 cases （ 28. 6% ）. Conclusion Sequential application dexamethasone and indomethacin suppository showed assured curative effect to prevent fever after splenectomy for Wilson＇s disease and to reduce complications remarkably.
出处
《肝胆外科杂志》
2007年第4期260-262,共3页
Journal of Hepatobiliary Surgery
关键词
肝豆状变性
脾切除
激素
吲哚美辛
发热
Wilson＇s disease
Splenectomy
Dexamethasone
Indomethacin
Fever
